We used the European Surveillance of Congenital Abnormalities Classification (EUROCAT) [ 22] to categorize CAs as minor and major, and excluded chromosome aberrations, genetic syndromes and microdeletions, teratogenic syndrome.
Other higher-order aberrations, up to fifth-order aberrations excluding coma and spherical aberration, were also higher in the LASIK group 3, 6 and 12 months after surgery (p<0.01).
But, as a service to the nation, I've taste-tested all the Marmite products currently available (which, thank God, excludes the aberration that was Marmite-flavoured chocolate), so you don't have to.
The study group excluded individuals with chromosomal aberrations.
Children with congenital heart defects, immune deficiency, or chromosomal aberrations were excluded.
Infants with congenital malformations or chromosomal aberrations were excluded from the analysis.
Submicroscopic aberrations were excluded using microarray-based comparative genomic hybridisation (array-CGH) (array(1 22)×2,(X,Y)×1). Osteogenesis inperfecta was ruled out in further tests.
Forty-three infants born with congenital malformations or chromosomal aberrations were excluded from the study and the remaining 2,487 infants were included in the analyses.
Children with additional medical conditions that may contribute to neurologic dysfunction such as Down syndrome, fragile-X syndrome, significant premature birth (<34 weeks of gestation), birth asphyxia, cerebral palsy, Rett syndrome, and children with other chromosomal aberrations were excluded.
To have a unique profile of aberration status, we excluded simultaneous occurrence of different kinds of aberrations (e.g. deletion and duplication) at the same locus.
