"The video is what really gives the paper that exciting edge; the data source was new," he says.
"The ups usually happened when you saw something exciting in the data, something that could potentially be a signal" for the Higgs, he says.
All referees find your experimental observations exciting and the data of high quality.
"The exciting thing about the data on linaclotide is that it improves both of those symptoms," he said.
While this market has taken off, there are a number of other possible (and more exciting) uses for the data.
Recently, the exciting data from the phase III BOLERO-2 trial was released, demonstrating a significantly greater PFS with the combination of exemestane and everolimus compared with exemestane alone [ 36].
Dr. Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, said trials now under way under the sponsorship of the National Institutes of Health were showing that adults who got only a single dose were protected within 8 to 10 days, which he said "corroborates and confirms the exciting data" reported in the Australian study.
Never-the less, exciting data have emerged from a phase II clinical trial of givinostat (ITF2357), an orally bioavailable HDACi, in patients with JIA (ClinicalTrials.gov NCT00570661).
Based on exciting early data, the BEATRICE trial enrolled total 2591 patients with early stage breast cancer, divided them into two groups – one group to receive standard adjuvant chemotherapy and monitor, and the other to receive standard chemotherapy (either anthracycline or taxane based on investigator's choice) + 5mg/kg weekly equivalent bevacizumab, and followed by bevacizumab maintenance.
Finally Djillali Annane (Garches, France) presented his exciting preliminary data on the results of the Phase III multi-centre, randomised, double-blind trial of low dose hydrocortisone (50 mg, 6 hourly) and fludrocortisone (50 μg/day) in septic shock.
