Sentence examples for excision cell from inspiring English sources

A variety of experimental endpoints including excision cell survival, lung colony curability, tumour regrowth delay and i.m. tumour curability following MeCCNU alone and combined with gamma-radiation, were used to define the MeCCNU cell survival curve down to "tumour cure" level in previously untreated i.m.

Using both excision cell survival and growth delay endpoints, only approximately 25% of tumours were significantly resistant to the test dose, suggesting that many tumours resist the effects of the drug for reasons other than the presence of inherently drug resistant cells.

Excision cell-survival assays performed 24 h after drug administration showed that in vivo sensitivity to m-AMSA progressively increased as pigmentation level decreased, but that m-AMSA drug levels measured 24 h after treatment were much lower in amelanotic than in melanotic lines.

After excision, cells differentiated unless maintained in the presence of LIF.

For Cre-mediated transgene excision, cells were treated with 500 nM of 4-OHT.

The XPD gene encodes a DNA helicase, essential for transcription initiation, nucleotide excision repair, cell cycle control, and apoptosis.

Immediately after excision single cell suspensions were prepared for flow cytometry, or alternately tumours were frozen in liquid nitrogen and stored at –80°C.

Helicases are implicated in a wide range of processes such as recombination, replication and translation initiation, double-strand break repair, maintenance of telomere length, nucleotide excision repair, cell division and proliferation [ 18].

By comparing the results for wild-type and excision-deficient cell lines, it was clear that excision repair can eliminate most of the lesions that can be repaired by postreplication repair.

These results are consistent with the model that the DNA double-strand breaks that are produced in UV-irradiated excision-deficient cells occur as the result of breaks in the parental DNA opposite unrepaired DNA daughter-strand gaps.

These findings suggest that the absence of a marked delay in DNA synthesis observed in RM may be responsible for the inhibitory effect of RM on the survival of UV-irradiated excision-deficient cells.