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This strain has the ability to excise these SCC elements either independently or together, but excision at an alternative site was also noted previously [7].
Complete excision at the base of the ligamentous insertion of the cyst assures a minimal rate of recurrence.
The folded furin zymogen initially undergoes an autocatalytic excision at the primary Arg-Thr-Lys-Arg107↓Asp108 site [14], [15].
Local melanoma can be cured by wide surgical excision at its early stage [2], but metastatic melanomas are usually incurable [3].
Through this P-excision screen, we obtained multiple lines in which excision at the CG1514 insertion site had occurred, but in all cases a small fragment (25 45 bp) of residual P-element was still present at the excised locus.
Analysis of UPF2 null livers 21 days post pIC revealed efficient excision at the Upf2 locus resulting in the expression of the truncated non-functional form of UPF2, as reported previously (Figure 4C,D; [13]).
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Only half the patients had completely excised tumours (with clearance of >5 mm at all excision margins) at operation, and recurrences appeared early.
By this point, Heizer had been in New York for a couple of years, going to Max's, mixing Soyalac for the baby, and working intensively on "negative paintings," canvases with geometric excisions at the edges.
As only a few cells in a given tubule tended to show loss of Pten immunoreactivity at 4 10 wks post-OHT exposure, it suggested that Pten excisions at the epithelial stem cell level may have been infrequent.
Epithelial proliferation rate in colonic biopsies, expressed as labelling index, was determined with 5-bromodeoxyuridine and immunohistochemistry. Biopsies were taken from the midsigmoid at time of polyp excision and at the end of the intervention period.
The selection for plasmid integration occurs at 42°C in the presence of chloramphenicol while plasmid excision occurs at 28°C in the presence of kanamycin.
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