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In order to analyze cross reactive potential, Fytili et al. 2008 [13] tested in vitro the T cell stimulation capacity of an HCV wild-type epitope NS31073 (CINGVCWTV) and nine other epitopes derived from this original, each one being an alanine exchange variant, against a cell population previously exposed to the original epitope.
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In the native codon exchanged (NCE) variant, the V-region codons were replaced with those used in naturally derived human antibody genes.
The ATP-dependent chromatin-remodeling complex SWR1 exchanges a variant histone H2A.Z/H2B dimer for a canonical H2A/H2B dimer at nucleosomes flanking histone-depleted regions, such as promoters.
This allows us to not only evaluate the degree of thermal comfort of the occupants in accordance with ASHRAE standards but also to carry out future comparisons between different thermal exchange system variants arising from the HVAC system.
iWe consider the bandplan setting for fiber-to-the-exchange, mask variant B, and un-notched mask M2, which would not be used in practice in this form due to the high ingress noise into ADSL lines but serves our purpose to imitate the insightful scenarios found in Section 'DSM based on successive SINR-approximation and geometric programming'.
Direct sequencing confirmed that this product corresponded to the exchanged mRNA variant E22-E24-E24 (Fig. 2D).
HbA1c assays were performed by ion-exchange HPLC (Variant Hemoglobin A1c Program; Bio-Rad Laboratories, HerCAles, CA, USA).
First, interpretation could be significantly improved by sophisticated and transparent exchange of variants associated with clinical indications.
The unique and defining characteristic of these remodelers is an ability to exchange H2A variants into and out of nucleosomes.
This suggests the possibility that H2A, if not regulated by PTM, may be controlled by exchange of variants such as H2AX, H2AL1, H2AL2 and H2BL1 previously reported [ 27, 28].
The arms of each palindrome show 99.94%99.997%% similarity in alignable sequence, as a result of frequent gene conversion activity [Rozen et al., 2003], in which nonreciprocal exchange homogenizes variants that arise through the slow processes of nucleotide substitution and insertion/deletion.
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