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The CDS of the other HLS are smaller, but they nevertheless support the notion that exchange of sequences between host and viral genomes may be an evolutionarily frequent event.
Thus, the GC trend curve profile suggests that a reciprocal exchange of sequences took place between both chromosomes.
Only five separate sequence exchanges were identified amongst RH, DM and HB R2 paralogs (Additional file 5) indicating that members of the RH/DM/HB ortho-haplotype have not been subject to frequent exchange of sequences and have evolved mainly through the accumulation of point mutations at hypervariable sites.
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The transfer or exchange of sequence information most certainly occurs among the centromere regions of non-homologous chromosomes.
Two of these extensions, developed over the past year, allow the exchange of sequence alignments and protein structure data.
This issue is complicating annotation, data merging and exchange of sequence variants in genetic and genomic analyses.
In homogenization, gene conversion causes concerted evolution in gene families through reciprocal exchange of sequence between paralogs [ 1].
Instead of full genomes resulting from exchange of sequence between the parental genomes, rearranged (deleted) sequences that were recovered by PCR support this recombination event.
Additionally there is support for the occurrence of interlocus exchange of sequence motifs [ 45, 46], which could also lead to misleading BLAST results.
Second, the recombination barrier limiting the exchange of sequence between inverted and non-inverted alleles may not be as strong as generally supposed.
The exchange of sequence between superfamilies produces structural variants that can eventually compete with each other and evolve as separate entities.
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