Sentence examples for exchange gdp from inspiring English sources

Rather, our interpretation is that subunits are released following GTP hydrolysis, and then they exchange GDP for GTP and reassemble into new protofilaments, all on a time scale of 7 s.

After gel filtration, protein was concentrated and nucleotide exchange (GDP or GTPγS) was performed as described above for lipidated Gαi1.

The grp2/SOS complex then promotes inactive Ras to exchange GDP with GTP and enters an activated state.

Rab GTPases are recruited to the COPII vesicles and upon activation in the presence of GE Fs exchange GDP to GTP 29.

Because plant Gα subunits spontaneously exchange GDP for GTP, in the absence of the 7TM-RGS, the Gα subunit is GTP bound (i.e. activated) and the Gβγ dimer is freed.

When phosphorylated (Fig.  2c), EIF2A loses its ability to exchange GDP and GTP, impairing the formation of a complex with the EIF2B subunit and thus preventing translation initiation [ 36].

This phosphorylation event suppresses global protein synthesis by inhibiting eIF2B, the GEF that exchanges GDP for GTP on eIF2, thus preventing eIF2 rebinding to tRNAi Met and forming additional ternary complexes.

GDP bounded Arf1p is activated by guanine exchange factor (ArfGEF) by exchanging GDP with GTP, which triggers the formation of COPI-coated vesicles (Poon et al. 1999).

Gα exchanges GDP for GTP and, once dissociated, the Gα-GTP and Gβγ subunits can activate distinct downstream targets and second messenger generating systems within the cell.

In that case, which molecule is responsible for exchanging GDP for GTP in Gtr2?

GDP-bound inactive transducin exchanges GDP for GTP, and GTP-bound active transducin increases the activity of cGMP phosphodiesterase.