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However, increased levels of ROS are excessively damaging all kinds of biomolecules leading to degeneration of biological systems.
A excessively damaging build-up of O2− may be avoided by NO itself scavenging some O2− to form ONOO− (peroxynitrite) which readily becomes protonated and finally decomposes to harmless H+ and NO3− (Beligni and Lamattina, 2002).
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Even if only one of the constraints explained above is violated, the quality of the forged image will be excessively damaged.
The prime minister this morning chaired a meeting of senior officials to discuss the impact on the UK of possible Greek exit from the eurozone - and to take steps to ensure British banks and companies would not be excessively damaged.
The S-phase transition in fibroblasts usually results in reparable DNA damage, visible as low numbers of large γH2AX puncta; we only classified cells expressing 7 or more puncta as excessively damaged.
Fission, on the other hand, is the mechanism that allows the continuous creation of small mitochondrial fragments, which can either re-fuse with the network or be segregated out if they have become excessively damaged.
Such a checkpoint mechanism could, for example, (i) prevent excessively damaged partially replicated molecules from undergoing a full round of replication or (ii) assist HSP-initiated transcription to pass the replication fork, preventing possible head-to-head collisions between mtDNA transcription and replication.
Also, it has been reported that yeast cells are excessively sensitive to DNA damaging agents if there exist mutations in NUP60 (Nagai et al., 2008).
Try not to use straighteners, curlers or other chemical products such as dyes excessively, these can damage your hair if used too frequently.
But if it is released excessively, it will damage the membrane structure, protein and DNA through various channels and lead to neuronal necrosis or apoptosis [ 24], which eventually damage the nervous system.
Threshing can damage excessively dry or wet seeds.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com