Sentence examples for excessive virulence from inspiring English sources
The excessive virulence of most conventional tracers, however, impedes their utility in revealing and genetically perturbing cellular function on long time scales.
The difficulty in treating these infections is not due to any excessive virulence of the organism per se but rather to its antimicrobial drug resistance.
"So not excessively excessive.
For example, excessive inflammation might alter virulence-exploitation relationships by: (i) increasing the rate of host death even when the rate of parasite killing also increases (Graham et al. 2005a; Day et al. 2007); (ii) disproportionately killing transmission-stage parasites; or (iii) altering investment in transmission-stage parasites.
Clinically, EBOV infection can result in exaggerated inflammatory responses and multiorgan damage, although the pathogenesis (including the inflammatory pathogenesis) and the viral virulence factor(s) involved in the excessive inflammation induction and viral pathogenicity are largely unclear.
This observation uncouples HIF-1α induction from aggressive tumour invasiveness and implies that excessive host cell oxidative stress diminishes Theileria-infected macrophage virulence.
It is well-established that in the sub-acute stage of CVB3 myocarditis (day 4 14), excessive immune responses become the dominant damage factor instead of virus virulence [30].
Recognising this, several authors have argued that immunopathology is a major complication for the parasite-centric trade-off model of virulence evolution (e.g., [ 7, 18, 19]), and the implications of excessive immune responses for standard models of the evolution of virulence are now beginning to be subject to theoretical investigation (e.g., [ 20, 21]).
In conclusion, the data suggest that there are clone-specific effects relating sub-lethal virulence to transmission and importantly that in the case of the Thai clone, that excessive anaemia may be a fitness cost for virulence evolution.
