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Multiple incisions and excessive opening should be avoided to prevent damaging the ovarian cortex, functional ovarian tissue and the hilum.
Excessive opening of voltage-dependent Ca2+ channels could accompany NMDA receptor-induced membrane depolarization and contribute to toxicity mediated by already large Ca2+ influx through NMDA receptor controlled ion channels.
Excessive opening of mitochondrial pores (MPTP) leads to swelling of the mitochondrial matrix, rupture of the outer mitochondrial membrane (OMM) and a ROS burst, possibly caused by loss of antioxidants [ 10, p. 440].
In order to simulate their behaviour, we made the following changes of the logical functions: Excessive opening of mitochondrial pores (MPTP) leads to swelling of the mitochondrial matrix, rupture of the outer mitochondrial membrane (OMM) and a ROS burst, possibly caused by loss of antioxidants [ 10, p. 440].
KATP channels are also expressed in the heart and on vascular smooth muscle, and excessive opening of vascular KATP channels in sepsis (due to a fall in the ATP/ADP ratio, pH or oxygen tension, or a rise in intracellular lactate) leads to hyperpolarization of the cell membrane, a blocking of the calcium influx, and loss of vascular tone (contributing to the "vascular paresis" of septic shock).
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Using a simplified stability analysis, the required restraining stiffness to achieve a stable inelastic response and avoid excessive gap opening is provided.
The poorly controlled application of the "selection system" and its variants has resulted in excessive canopy opening and abundant colonization by pioneer species of little commercial value.
An experimental investigation on the strength and behavior of reinforced concrete beams with shear openings was carried out to evaluate the efficiency of using CFRP sheets for control local cracks around openings and to resist excessive shear stresses in the opening regions (Abdalla et al. 2003).
In case of too wide of a mouth opening, or excessive mobility of the jaw and mandible deviation during opening (with excluded suspicion of subluxation), the exercises are limited, and straightening of the opening pathway are recommended.
Watch out for the presence of redness, excessive drainage and unnecessary opening of the wound.
Also in this example, the poor ventilation during winter, with limited window opening, lead to excessive CO2 concentration as a trade of for relatively acceptable indoor temperature.
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