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In the myocardium, a significant ROS production occurs in the mitochondria and when it is excessive, it contributes to oxidative stress and mitochondrial dysfunction.
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In excessive amounts, it contributes to an illness known as methemoglobinemia in infants.
FN is an important factor in the ECM and excessive synthesis of it contributes to glomerular basement membrane thickening and glomerular sclerosis.
Fluid challenge, which has been described years ago [65], is a reliable test for fluid responsiveness, but, since it requires the irreversible administration of fluid, it contributes to excessive fluid administration.
This week, Orient Today, a newspaper in Zhengzhou, the capital of Henan Province, reported that hospital records indicated that Mr. Guo's drinking had been so excessive that it had contributed to his death.
Thus, it is concluded that, while appropriate NMDAR activation is essential for neuronal survival and physiological functions, excessive activation contributes to pathological changes including cell death.
Others have warned the new rules may be vulnerable to a legal attack, since the CFTC hasn't shown conclusively that excessive speculation contributes to rising commodity prices.
Scientific studies indicate that the intake of dietary fat and saturated fats in the modern Western diet is excessive and contributes adversely to health, lifestyle, and longevity.
"Drinking at these excessive levels contributes to a range of medical conditions including cancers, cardiovascular diseases, diabetes, gastro-intestinal diseases, neuropsychiatriac disorders as well as accidental injury and video".
These results demonstrate that increased bone resorption due to excessive osteclastogenesis contributes to the skeletal pathologies in MLII.
Excessive testing contributes to the growing problem of waste in healthcare and increased patient burden in diabetes management.
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CEO of Professional Science Editing for Scientists @ prosciediting.com