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Excessive inflammatory reaction such as neutrophil activation has been observed in pregnant women whose offspring had restricted fetal growth, but the association between white blood cell (WBC) counts and SGA birth has not yet been assessed.
However, excessive inflammatory reaction promotes injury e.g. through neutrophil-derived superoxide production [47].
However, excessive inflammatory reaction may also contribute to tissue damage by enhancing macrophage infiltration, which increases tissue free radical load leading to further tissue injury [36].
Consequently, the host is protected against a destructive attack on its own tissue, or an excessive inflammatory reaction towards an antigen that poses no threat.
We find that in immunocompetent hosts TB progression is not a direct consequence of high Mtb loads, but rather, is a result of excessive inflammatory reaction developed in Mtb infected lungs.
In a population, where infections are prevalent (in the Ghanaian population 85% of all participants and 100% under 30 years of age are infected with P. falciparum), decrease in downregulatory capacity might have a detrimental impact on the course and outcome of infection as a result of excessive inflammatory reaction [24].
Similar(45)
However, clinical application of its potent bone induction ability may be hampered if its use is accompanied by excessive inflammatory reactions.
2) GL might protect organ function by regulating excessive inflammatory reactions.
Upregulation of PTX3 may function to control the complement cascade in the pregnant animal and prevent excessive inflammatory reactions.
This interaction between immune and central nervous systems is important for preventing excessive inflammatory reactions in intensive care unit patients.
Regulation of the excessive inflammatory reactions might be a major mechanism by which GL exerted its protective effect.
More suggestions(16)
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