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It is thus possible that HOCM solutions >800 mosmol/kg H2O become concentrated in tubules to such an excessive extent.
In attempting to reconcile these apparently contradictory findings, we speculate that the majority of patients in this study may have suffered from non-acid reflux or experienced excessive proximal extent of reflux episodes [ 10].
Its leading causes -- the use of tobacco primarily and, to a lesser extent, excessive alcohol consumption -- are totally preventable.
G cat is estimated to reveal the average level of CMP severity for all studied households, but it cannot indicate to what extent excessive payments affect the said households.
Despite overexpression of the mutant protein which could cause excessive secretion, the extent of its intracellular retention was 5.5 ± 1.3%, which was even higher than for wild-type dCREG-V5His (1.1 ± 0.1%; p = 0.029).
In addition, the association between ScysC and AIx remained independent after adjustment to eGFR suggesting that an increase in ScysC concentration might not only reflect impairment in renal function but also to a certain extent excessive arterial stiffness.
Finally, larger numbers of patients would be needed to study the extent of excessive alcohol use in this population.
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