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The final questions are: wheter or not a dispersion of 5S rDNA is only a byproduct of rapid genomic change, is there any possible contribution to the host genome worth maintaining such a high number of copies, or are the excessive copies most likely sentenced to pseudogenization and elimination?
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Some care is also taken not to have excessive copying from one issue or one volume of the periodical.
Prior to 1968, NLM had no express policy on copying limitations, but endeavored to prevent "excessive copying". Generally, requests for more than 50 pages of material will not be honored, though exceptions are sometimes made, particularly for Government institutions.
Moreover, if the ease of copying coincides with ease of learning, this leads to excessive copying, as in pure patches.
Note that excessive copying only occurs in patchy environments, where copying is easy and unselective foraging can spread quickly through groups.
However, while we do not find that copying can reduce the acquisition of new information in groups, we do find that the mediation of copying by individual experience and selectivity is crucial, as revealed by excessive copying.
For known deletion or insertion of repeats, the excessive copy in the reference can be substituted by "-", which allows for mapping of the same number of or fewer copies.
Full GPU residency of an algorithm helps to offload the CPU and eliminates excessive memory copies via the PCI-e bus.
The excessive multi-copies spraying in the network causes serious congestion and exhaust nodes' buffer space, thus influences the performance of transmission dramatically.
Possible functional consequences of excessive 5S rDNA copies.
Shlien, A. et al. Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome.
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