Sentence examples for excesses of variation from inspiring English sources

We tested the 18 gene regions for deficiencies or excesses of variation.

We used the HKA test for excesses of variation in SDHA gene.

Moreover, in a search for rare variants in idiopathic epilepsies, Klassen et al. (2011) resequenced protein coding regions of ion channel genes and did not find an excess of variation compared to controls.

Using statistical simulations, it is possible to generate synthetic exposure time lines mimicking lack or excess of exposure variation.

Detailed analysis of TERT and TERC in Ashkenazi centenarians showed an excess of genetic variation in both genes in the centenarians and identified a TERT haplotype associated with extreme longevity (Atzmon et al. 2010).

a k (selection parameter) values from MLHKA test; k<1 means a reduction in polymorphism while k>1 means an excess of nucleotide variation; b p values for the MLHKA test; c likelihood (sum of deviations) for multi-locus HKA test; d p values from demographic coalescent simulations for multi-locus HKA; e not analyzed.

These data indicate that the excess of sequence variations in individuals with extreme phenotypes reflects an enrichment of functionally significant variants.

In signal limited applications use of this algorithm to remove one source of excess variation is beneficial.

This may be a consequence of excess variation in sample size (N) and depth of coverage per site, which can result from variation in the amount of DNA associated with each genotype loaded into a pooled sample.

The amount of variation in excess LOS and costs of AEs and preventable AEs caused by hospital level was indicated by the Intraclass Correlation Coefficient (ICC) [ 31].

MK tests [ 35] reveal a pattern of variation consistent with excess non-synonymous polymorphism for 3 of the 4 regions (Table 4).