An excess of female subjects (67%) in both subgroups were present.
29, 30 Such an excess of COPD subjects in the unscreened controls would be expected to dilute the effect of protective variants (such as the FAM13A gene) given comparable allele and genotype frequencies in COPD and lung cancer cases compared with unscreened controls (see Figure 1 and Table 3).
Many studies have identified, in the Northern Hemisphere, an excess of births of subjects with schizophrenia during the winter and early spring, especially between December and April [ 11].
In general, finding an excess of Rhesus negative subjects among patients with endometriosis suggests a genetic predisposition.
The age distributions of cases and controls were somewhat similar although there was a slight excess of younger control subjects, and cases were more likely to consume high amounts of tobacco.
Sony's underinvestment in security may cost in excess of $100 million, and subject the firm to years of lawsuits from past and current employees over stolen private data.
Married couples with combined incomes in excess of $239,950 are subject to "phaseout" deductions meaning they can't claim as much in deductions as their total income climbs beyond that level.
Businesses with annual taxable gross receipts in excess of $1 million are subject to the annual minimum CAT of $150 plus apply a CAT effective rate of.26% on receipts above $1 million on a quarterly basis (with a $250,000 quarterly exclusion).
The notable exception to this pattern was the response observed in the 160603/902 trial, where rHuPH20 was administered in combination with human IgG in subjects with primary immunodeficiency and induced a durable rHuPH20-binding antibody response with titers in excess of 5000 in five subjects.
Thus, when variants within a gene affect risk there is a consistent phenomenon that means that, over a wide a range of genetic models, one expects to observe an overall excess of rare alleles amongst subjects having a rare phenotype.
