Sentence examples for excess of significant from inspiring English sources

Nevertheless, even if the significance of these probes was moderate, we observed an excess of significant p-values in comparison to what we could expect under the null hypothesis of no association in that region.

The cytokine-cytokine receptor interaction pathway, was the only pathway showing an excess of significant findings in fetal data.

Fetal data, in contrast to maternal data, had neither highly significant associations nor an excess of significant associations in genes involved in the complement and coagulation pathways, but did have an excess of significant associations in infection/inflammatory response PTB pathways.

For each permutated dataset, a chi-squared test was performed to ask if either the random gene or selection-candidate SNPs showed an excess of significant tests relative to each other.

We used the visual approach [26] to determine whether there was an excess of significant associations by comparing the P values for the association tests to those expected under the null distribution using Quantile-Quantile (QQ) plots.

Multilocus analyses on pathways with an excess of significant associations for either allele or genotype tests (identified by Z tests analyses) revealed a statistically significant two locus model in the complement and coagulation pathway in maternal data after excluding the single most significant tPA marker (rs879293) (Figure 1).

Considering the number of assays performed, IL4 showed an excess number of significant SNPs associated with asthma (4 out of 5), while a larger gene such as CLCA1, with 23 SNPs, showed no significant SNP associations.

When ZHP is precipitated with considerable excess of H3PO4, significant amount of –OPO3H2 groups is formed (compare Fig. 4a and d).

To exploit any signal arising from the excess of nominally significant SNPs in the GWAS, we used ALIGATOR [16], to identify functional categories that were enriched for association signals.

However, across the network of FDA data, we found no signal of an excess of statistically significant results (p=0.24).

This is problematic because studies published in journals suffer from an excess of statistically significant findings [ 10].