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Children diagnosed with ADHD tend to have an excess of low frequency (theta) brain waves and fewer high frequency (beta) waves in certain regions of the cortex, as detected by EEG (Figure 2).
In addition, emerging data demonstrate associations between other forms of CV disease including atrial fibrillation (AF) and nonischemic myocardial fibrosis and exercise exposure in excess of low to moderate levels [7, 8].
The significant negative values calculated for Tajima's D value signifies an excess of low frequency polymorphisms, indicating population size expansion or positive selection.
A very strong bias would be expected to generate an excess of low MAF SNP in breeds not represented during the SNP discovery process.
A negative Tajima's D signifies an excess of low frequency polymorphisms, and indicates a population size expansion and/or positive selection, or negative selection.
Thus, we verified whether the remaining 36 SNPs were showing an excess of low p-values when compared to a typical distribution of p-values expected for 36 true null hypotheses.
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Li, Y. et al. Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants.
If the chromosome 1 region corresponds to a relatively recent species-wide sweep, there should be an excess of low-frequency alleles; this is indeed what we found.
Negative values of Tajima's D were observed in both populations suggesting an excess of low-frequency polymorphisms.
The underconnectivity theory hypothesizes underfunctioning high-level neural connections and synchronization, along with an excess of low-level processes.
The underconnectivity theory of autism hypothesizes that autism is marked by underfunctioning high-level neural connections and synchronization, along with an excess of low-level processes.
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