Mr. Malmsten and Ms. Leander became symbols -- in magazine articles, business journals and corporate speeches -- of the excess of dot-com companies.
It's part of a continuum that started with the excesses of the dot com bubble, culminated with huge changes on Wall Street that hurt the ability for smaller companies to go public and the desire for entrepreneurs to take them public, and has been rippling through several trends like partial liquidations, secondary exchanges and buyouts.
The number of peptides was determined by conjugating them with a large excess of streptavidinylated quantum dots for screening purposes.
Most venture capitalists say the trouble began amid the excesses of the dot-com era.
Mr. Heiferman is eager to distinguish himself from the excesses of the dot-com boom years.
But Mr. Greenberg says he recalls the naming as a signal event in his own understanding of the excesses of the dot-com era.
And Mr. Paulson sat at Goldman's helm during the excesses of the dot-com bubble, selling vast numbers of subpar companies that promptly crashed with the market.
Sergey Brin, president of Google, took the stage and defended his company's decision to continue what many now consider symbolic excesses of the dot-com era like free meals and massages for employees.
The company in some ways typified the excesses of the dot-com era: It went so far as to advertise with stickers on apples and bananas, sent Jeeves-type butlers to busy public places at lunch and leased tens of thousands of square feet of office space, expecting no end to its growth.
Since 2000, the artist has installed in excess of 70 pieces of work dotted around Hong Kong; the artist has declared the third wave undertaken in city, with 50 works, "probably my most accomplished city invasion wave".
Gene expression data points in relation to their statistical significance are presented as volcano plots in Figure 2C, which shows an excess of significantly down-regulated genes (green dots) over significantly up-regulated genes (red dots).
