Sentence examples for excess of bases from inspiring English sources

Finally, Figure 2B demonstrates that the sequencing of RRLs successfully produced an excess of bases with high coverage (≥8x) compared to what is expected without any genomic reduction procedure.

Earlier, Eemian 125kyrs ago was sig warmer — Gavin Schmidt (@ClimateOfGavin) 25 Jul 13 11) At neither of these times is there any evidence for CH4 emissions or concentrations in excess of base pre-industrial conditions.

Another technique introduced in [102, 103] allows interference suppression with smaller excess of base station antennas.

This type of control works only if the difference in acidity is large enough and no excess of base is used for the reaction.

The deviation from randomness is presence of a small excess of base changes closer than predicted, which are presumably due to clustered mutations, as identified by Drake [64].

Katz and Burge proposed that the excess of base pairing in mRNA molecules is due to selection for stable mRNAs.

‡ It should be noted that, although the reaction time can be significantly decreased by adding a large excess of base, all reactions were carried out with 2 equivalents in order to minimise waste.

Detecting a single damaged base in a vast excess of regular bases in the genome amounts to the proverbial task of searching a needle in a haystack, and this is not helped by the fact that the lesions addressed by BER do not usually cause notable distortions to the DNA helix.

The initial step involves a specific DNA glycosylase finding its substrate lesion via one- and three-dimensional diffusion in the midst of a vast excess of canonical bases that in many instances are structurally similar to the damaged base.

Benefits of this approach include (i) rapid removal of the roughly million-fold molar excess of unaltered bases from the sample, (ii) reduction in the length of enzymatic incubations and the number of steps, (iii) elimination of high temperature incubation, (iv) a very clean chromatographic separation, and (v) rapid elution of the analyte and correspondingly greater throughput.

The studies by Bustamante et al. and Voight et al. identify significant signatures of selection on genes involved in transcription (Cluster I) while our findings highlight that these categories harbour an excess of polymorphic bases are likely to be unique to humans.