Post-menopausal osteoporosis is a disorder of excess skeletal fragility, due partly to changes in bone microstructure.
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1, 2 Whether or not the excess mortality of the fragility hip fracture persists over time is not yet clarified.
Fragility fractures cause excess mortality, substantial morbidity, and related health and social service expenditures in older people. 1 2 Risk of fracture is higher in institutionalised older people than in community dwelling older people of the same age, reflecting a greater risk of falls and lower bone mineral density.
The increase of absolute values of all bone parameters was not in proportion to excess weight, leading to relative bone fragility [ 58].
However, fragility contributed little to the excess accidental injury risk under the age of 30 59 years population [43].
In male patients presenting with osteoporotic fractures, major causes of skeletal fragility, such as hypogonadism, glucocorticoid excess, primary hyperparathyroidism and alcohol abuse, can often be identified (Vanderschueren et al 2000).
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The risk factors of fractures related to osteoporosis are age, prior fragility fracture, parental history of hip fracture, smoking, use of systemic corticosteroids, excess alcohol intake and rheumatoid arthritis [ 15].
These risk factors include but are not limited to age, a prior fragility fracture, a parental history of hip fracture, smoking, the use of systemic corticosteroids, excess alcohol use, rheumatoid arthritis, low body weight, etc., [ 10].
