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Within the network diagrams, we identified haplotypes belonging to heterozygous individuals (dashed lines) or to homozygotes (solid lines) and searched for exceptions to this expectation.
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Exceptions to this general expectation can plausibly be attributed to variations in amino acid substitution rates either across species at a particular time or during an elapsed time span for particular lineages.
Contagious cancers [Tasmanian devil facial tumor disease (DFTD) and canine transmissible venereal tumor (CTVT) (Morgia et al. 2006; Murchison 2009)] present unique exceptions to the expectation, based on these considerations, of reduced adaptive evolution in cancer cells.
There are exceptions to this rule.
There are no exceptions to this rule.
Are there any exceptions to this rule?
There have been exceptions to this practice.
There are notable exceptions to this, however.
There are of course exceptions to this.
There are exceptions to this conventional wisdom.
There are important exceptions to this trend.
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