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In this regard, more studies are needed to determine whether this alteration was an exceptional manifestation of DD-I teeth resulting from a specific mutation, or an artifact of specimen processing.
Therefore, alterations of microRNA expression are not exceptional but rather the rule in human cancer.
We did not find evidence of co-occurrence of the DNA repair and chromatin remodeling genomic alterations as observed in the capecitabine exceptional responders in the TCGA ER-positive, HER2-negative primary breast cancers, suggesting that coexpression of these alterations is uncommon.
The advent of microarray-based comparative genomic hybridization (array-CGH) has facilitated the analysis of chromosomal alterations in the cancer genome, providing pangenomic alteration profiles with exceptional spatial resolution in a single experiment [ 5].
There is also an emerging interest in identifying patients who have had an exceptional response to a therapy, and in evaluating these patients' cancers for molecular alterations that may account for the observed marked benefit 1.
"Nothing exceptional".
No alterations, no changes.
Two, exceptional.
Exceptional, unforgettable.
Exceptional stuff.
Exceptional kicking?
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