Unenhanced computed tomography (CT) is considered the best diagnostic test due to its excellent accuracy detecting ureteral stones.
CT is excellent in detecting perivalvular extension, with one series demonstrating 100%% sensitivity, using surgery as a reference standard [20].
They also demonstrated that DXA could not always detect defects in the regenerate and concluded that ultrasound was excellent at detecting these defects and therefore complemented DXA during limb lengthening, reducing the need for plain radiography [10, 13, 18].
The imaging tests were found to be excellent for detecting and confirming grade II and III lesions.
CT and MR imaging are excellent for detecting mass lesions and for following their size during therapy.
However, while these technologies are excellent in detecting traits in populations and revealing population structure [ 36], they are less informative in defining introgression borders and their content.
Although excellent for detecting global CIN changes, even the most advanced FISH strategies cannot accurately measure somatic mutations throughout the genome.
While CT is excellent in detecting unresectable tumors (>90% accuracy), it frequently understages true tumor extent and even with early helical CT, the accuracy for assessing resectability was only around 70% [ 4].
It is necessary to note that in our study, 3q26 was found to be excellent at detecting both cancer and high-grade lesions (CIN2/3), however, it did not meet our criteria established for CIN1 cases that required to detect copy gains in ≤ 10% of samples (3q26 detected gains in 30% of CIN1 cases).
Along these lines, we are currently testing the different HMMs and MRCs with the Pea aphid genome, where they have proved excellent for detecting and annotating new caps ranging from pepsins and ddi host genes to different LTR retroelement lineages (manuscript and database update in preparation).
