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Consequently, a large heterogeneity of PK parameters was found, exceeding a twofold variation (Table 1 and Figure 3).
According to a more recent publication a dose-related increase in micronuclei frequencies (e.g. trend test) which exceeds statistically significantly the upper limit of the historical and concurrent negative control (chi-square or Fisher's exact test) or at least a twofold increase over mean control micronuclei frequencies are required for a positive call.
Voice networks supported a twofold increase in normal loads before a busy signal started to implode.
A twofold increase in liver cholesterologenesis rate was also noted.
Since 1998, the amount of money raised in America has more than tripled, compared with a twofold increase in Europe.
An epidemic of illegal drugs is scarring America, with a twofold increase in use and fourfold increase in deaths in the last decade.
The replacement of argon by nitrogen leads to a twofold increase of the delay.
The current showed a twofold increase after irradiation of UV light for 20 min.
Traveling to Las Vegas is associated with a twofold increase in risk compared to traveling elsewhere.
The result was a twofold increase in the mean average precision.
Live-cell confocal microscopy revealed increased mitochondrial mass in NaBt-treated PC12-ND6 cells, which was quantified to a twofold increase by flow cytometry (Fig. 1a, b).
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