Exact(1)
Immunohistochemistry as a method for detecting protein expression in paraffin-embedded tissue has been shown to be both highly sensitive and specific (Zafrani et al, 2000), yet the specificity of an immunohistochemical test would never exceed the specificity of the antibody provided by the manufacturer.
Similar(59)
The model yielded a sensitivity of 68% and specificity of 89%, which exceeded the specificity of D-dimer assay tested by latex agglutination, ELISA, and immunoturbimetric methods (sensitivity/specificity of 63.2%/60.5 %, 97.4/21.1%, 97.4%/21.1 %, 97.4ctively).
The specificity of the model exceeded the specificity of any D-dimer method in tested in both the validation group as well as the entire cohort, tested by latex agglutination, ELISA, and immunoturbimetric methods which showed sensitivity/specificity of 63.2%/60.5 %, 97.4/21.1%, 97.4%/21.1 %, 97.4ctively (Table 2).
The specificity and sensitivity for the cellular immunoblotting assay was similar to those for the islet autoantibody assays performed in the individual workshops and exceeded the specificity and sensitivity of other T-cell assays validated at this time.
An alarm sounded if the value of the cumulative distribution function of a Poisson random variable with mean E t exceeded the desired specificity.
Interestingly, LC3, p62 and TDP-43 immunopositivities were not uniformly high in muscle biopsies from the 4 subjects with classic IBM history; rather, they showed a large range of labeling that spanned the entire spectrum of %FS values seen in the IBM group, with 3 of 4 subjects meeting or exceeding the 100% specificity threshold set for each of the three markers.
The four (of 12) subjects in the IBM group that met "definite IBM ENMCcriteriaia showed a large range of staining that spanned the entire spectrum of IBM %FS values, with 3 of 4 subjects meeting or exceeding the 100% specificity threshold set for each of the three markers.
Among the 3 subjects with IBM presentation (designated by open symbols in Figure 4), all 3 subjects exceeded the IBM 100% specificity threshold for LC3, 2 subjects exceeded the IBM 100% specificity threshold for p62, and 1 subject (#33, shown in Figures 3f-j) exceeded the IBM 100% specificity threshold for TDP-43.
Among the 3 pIBM subjects with IBM clinical history (designated by open symbols in Figure 6), all 3 subjects exceeded the IBM 100% specificity threshold for LC3, 2 subjects exceeded the IBM 100% specificity threshold for p62, and only 1 subject exceeded the IBM 100% specificity threshold for TDP-43.
Don't Exceed The IRA Contribution Amount.
By reporting the lower limit of the 95% CI, one can claim with 95% confidence that the actual sensitivity or specificity meets or exceeds the stated sensitivity or specificity.
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