In order to illustrate that this imputation indeed improves the performance, we trained two models one that discards examples with missing gene expression values, and the other that uses this regression-based imputation.
However, if there are training examples with missing or unknown values, the approach may not correctly work.
This procedure results in the assignment of a neutral value, which does not bias the prediction, for evolutionary conservation in examples with missing data.
Examples "Variables with missing values were hypertension (1%), smoking (10%), BMI (14%), plasma HDL cholesterol (19%), plasma LDL cholesterol (20%), and plasma triglycerides (16%).
For example, patients with missing surgery information were excluded.
For example, in model 4, with missing data excluded, the odds of infection increase by just over 30% for each additional lifetime partner, among female non-migrants (aOR 1.31; 95% CI, 1.20 1.43) and by over 60% among female migrants (aOR 1.62; 95% CI 1.36 1.92).
Now, in trivial examples of spacetimes with missing points such as the one offered before, flat spacetime with a closed set in the shape of Ingrid Bergman excised from it, one does not need any technical machinery to add the missing points back in.
Because our features are derived by integrating several databases, some of which are not complete, there are many examples and features with missing values.
This is also illustrated by Examples 5,6,7,8, etc, except the case of the missing SEM of X1 in Example 5. Dealing with missing data in statistics, especially in meta-analysis is a very important issue (e.g., [ 37- 39]).
An experimental application example of a database with missing data related to an accident that occurred in the BP Texas city refinery illustrates the effectiveness of the method.
Nevertheless, the result must be inspected by a human expert since, for example, a methanol molecule with missing hydrogen atoms could be mistaken for a carbon monoxide moiety.
