Using He, Be and Ar as examples, we predict by first-principles calculations that the electrophobic interaction drives He, Be or Ar to form a close-packed cluster with a clustering energy that follows a universal power-law scaling with the number of atoms (N) dissolved in a free electron gas, as well as W or Al lattice, as Ec ∝ (N2/3−N).
Then, using 2,077 unknown genes released in April 2007 as test examples, we predict their functions and evaluate ROC (Receiver operating characteristics) score with gene function association released in December 2008 as annotation standard.
As one example we predict that nearby metal surfaces can be used to increase the low intrinsic quantum yields of nucleic acids and make unlabeled DNA detectable using its intrinsic metal-enhanced fluorescence.
As an illustrative example, we predict sap flux for a forest in North Carolina, quantifying changes in water use with tree species and size.
For example, we predict that at least 200 probe sets of 11 probes per probe set will carry SNP variation in three or more probes on the human genome HG-U133 Plus 2.0 arrays.
For example, we predict that at least 302 probe sets will carry SNP variation in three or more probes on the mouse genome U74Av2 arrays with 16 probes per probe set.
For example, we predict that A. lyrata, B. distachyon, and M. truncatula, which have some of the largest FBX gene superfamilies, have at least 370, 312 and 240 FBX pseudogenes, whereas C. communis, P. patens, and M. esculenta, which have some of the smallest FBX gene superfamilies, have as few as 9, 17 and 18, respectively.
For example, we predict two such residues to be functionally important T331 and S444.
For example, we predict an important HRE to be present in exon 8 of the human pfkfb3 and pfkfb4 genes.
For example, we predict that cells will evolve to take up nutrients faster when under competitive pressure.
For example, we predict that subtypes H3N2 and H5N1 occur in Hunan, China, a province that has high swine density and was the geographic origin of subtype H5N1 viruses in clade 2.1 (38 ).
