As representative examples, we determined specificity as a function of ligand sequence-dependent affinity contributions by statistical analysis of peptide library screens for the AF6, ERBIN and SNA1 (α-1-syntrophin) PDZ domains.
To illustrate this property with concrete examples, we determined which FCSs in R89\R1 involved any of the 24 reactions occurring at scope distance 1 in Figure 4b.
In order to test if WDR66 expression correlates with prognostic markers in a separate validation set of ESCC examples, we determined WDR66 expression in an independent set of n = 25 ESCC examples using qRT-PCR (Additional file 1: Table S1).
Using human epidermal growth factor receptor 2 (HER2) as an example, we determined whether testing for a recently introduced biomarker was associated with the outcome of women with breast cancer.
As a first example, we determined the location of the N-terminus of two membrane-active amphipathic peptides, the 26-mer bee venom melittin and a de novo designed 15-mer D,L-amino acid amphipathic peptide (5D-L9K6C), bofh of which are antimicrobial and bind and act similarly on negatively charged membranes.
For example, we determined that although the total 18O composition of our synthesized compounds matched the predicted amount, the 18O composition of the individual species differed, indicating that the assumptions of either complete, or no P-O bond-breakage in POCl3 were not met.
For example, we determined the percentage of action potential trains (for trains of 1, 2, 3, 4, 5, 10 and 40 action potentials at 83 Hz) that could be detected at a 5% false positive rate during 1 second of data acquisition (i.e., such that when a time series is divided into subsequent intervals of 1 second length, 5% of these intervals will contain a false positive event).
As an example, we determined fold change gene expression differences for Neu initiated tumors.
For example, we determined a broad linear correlation of the bridging P O(R) bond length in monosubstituted dianionic phosphates and the p Ka of the substituent alcohol.
For example, we determined the highest and lowest temperatures attained and held for at least two consecutive time points by each subject.
For example, we determined the enrichment of the relative abundance of H3K27me3K36un for MCF7 against the average relative abundance of H3K27me3K36un across the 24 lines.
