The last several years have provided many examples of side effects, some life-threatening, that emerged only after many thousands of patients had taken a drug (notably the painkiller Vioxx).
Examples of side effects include bradycardia, QT prolongation, bronchoconstriction, hypersalivation, and hypermotility.
Examples of side effects include diarrhoea, immunotoxicity, embryo/foetal and prenatal toxicity, cardiovascular side effects, and hypersensitivity [ 43].
Prescribing of LMWH or fondaparinux during an estimated rivaroxaban treatment may indicate a change of therapy for example because of side effects.
For example, certain kinds of side effects may be correlated with certain drug indications simply because of the patient population treated, and indications will correlate with target genetics due to rational drug discovery and known biology.
For example, some misclassification of side effects as doxycycline- or ciprofloxacin-related may have accompanied the switch in medications.
Pregnancy, for example, poses a risk of side effects for the fetus and increased risks for the mother.
The feature vector of drug D is supposed to be represented as an M-dimensional binary vector: Φ D = d 1, d 2,..., d M T, where d k ∈ {0, 1}, k = 1,..., M. For example, Φ D) is a profile of side effects or chemical substructures in this study.
Hence, its potential still remains partially unexploited, largely because of a lack of general consensus and public concerns regarding the lack of effectiveness and control, poor reliability, and possible occurrence of side effects, for example accumulation of toxic metabolites and pathogens.
Often medically focused for example, PSA level, tumour status and medical control of side effects.
However, this difference may be attributed to the fear of side effects in DLB patients; for example, side effects due to autonomic dysfunction.
