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Examples of scoring according to staining intensity and the percentage of stained cells are shown in Figures 1 and 2. PSA progression-free survival and overall survival were the main end-points of the present analysis.
Detailed guidelines with examples of scoring are also given in the AMIPB.
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Twenty-four hours post-irradiation (the time required to clear TD lesions), the UVB-irradiated areas were biopsied and the basal layer keratinocytes were assayed for co-expression of proliferation (Ki67) markers and UVB-induced DNA damage (TD; see examples of scored keratinocytes in Supplemental Figure 4).
Example of scoring for quantification of EphA4, pTau and Aβ.
Throughout the scoring, examples of cores scored as 1, 2 and 3 were on hand for comparison as an "internal standard".
Yet, there are many examples of scores losing accuracy in particular patient populations, including patients with human immunodeficiciency virus [ 26], cardiogenic pulmonary edema [ 27], and trauma patients [ 28]; even APACHE-IV significantly under- or over-predicted mortality in 13% of medical conditions during its validation [ 10].
The detailed example of scoring matrix is provided in Additional file 7.
Figure 7 Examples of highly scored AgroSAR pesticides.
b Representative examples of worms scored which display the three characteristic stages of DA neurodegeneration in response to 6-OHDA.
Other candidates included DDC, MANEA, ZWINT, while ERG and SERPINA3 were examples of genes scored with decreased expression in LNCaP compared to CD26+ cancer.
An example of score calculation is available in supplementary Figure S2.
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