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The authors of the FDA guidance name four examples of derivation of the MID: "mapping changes in PRO scores to clinically relevant and important changes in non-PRO measures of treatment outcome", "mapping changes in PRO scores to other PRO scores", "using an empirical rule", and "using a distribution-based approach".
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Application and examples of the derivation presented here are provided in a companion paper.
Examples of such derivation from diffraction data are illustrated in Fig. 6. Figure 6 The plot of versus d 2(P, T) for X-ray diffraction data on nano-Ni.
Therefore, these loci might represent odd examples of structural derivation in the absence of changes to expression profiles.
Examples of partial clonal derivation are also present in C. elegans: some precursors generate only, but not all, cells of a given type; other precursors generate all, but not only, cells of a given type.
The method is demonstrated through a series of examples, including derivations of analytical expressions for several common structures such as k-out-of-n: good and parallel systems.
Note that \(\mathsf{J}\) coincides with \(\mathsf{J}_{TCS}\). See Section 2 of the supplementary document Some More Technical Matters for examples of concrete syntactic derivations in justification logic.
Experimentally, it can be done, for example, by derivation of the real and imaginary values of the permittivity of solid adenine films in the deep ultraviolet spectral range.
The history of life offers plentiful examples of convergent evolution, the independent derivation of similar phenotypes in distinct lineages [1].
For example, as derivation of benefit, financial or otherwise, is one consequence of ownership, there is concern that benefits may only be made available to those who can afford to pay.
Such a full local time coverage has never been achieved in the previous wind measurements, and will enable, for example, the derivation of zonal-mean meridional winds for the first time.
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