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Hannun cited other examples of cancer "hot pockets" around the world – esophageal cancer is widespread in central Asia and northern China, kidney cancer abounds in eastern Europe and eastern Asia.
A few examples of cancer types are leukemia (white blood cell cancer), pancreatic cancer, lung cancer, and bone cancer.
There are examples of cancer mutations displaying a subgroup level of conservation, including EGFR-L858 position, which bears a conserved leucine in EGFR and ABL kinases, or a conserved aspartate shared in FLT3, KIT, MET, PDGFRα.
Among these genes, we found examples of cancer markers (MLANA) (also reported in Table 1), a recently described oncogene (OTX2) [27], and a gene used as a predictor of circulating tumor cells (ASGR2) [28].
Are there any examples of cancer cells that act as infectious parasites?
In this review we provide examples of cancer biomarker discovery using aberrant glycosylation in three areas.
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One is to ingest a large amount to data to train its AI platform about as many examples of cancers, diagnoses and outcomes as it can.
Two examples of cancer-specific measures are the European Organization for Research and Treatment of Cancer-QOL (EORTC QLQ-C30) and the Functional Assessment of Cancer Therapy general form (FACT-G) [ 17, 3].
In addition to the genome-based discoveries of "actionable" cancer genes, several examples of cancer-specific vulnerabilities are poised to yield new therapeutic advances and deserve discussion in this context.
As expected from the results of Table 1, most chromosomal regions associated with changes in expression levels actually correspond to gene inactivation patterns in cancer cells (373 up-regulated versus 744 down-regulated hits), striking examples of cancer-associated inactivation of gene expression being chromosome 17 and chromosome 3.
Alternative splicing is often deregulated in cancer, probably as a consequence of quantitative alterations in the levels of expression of splicing regulators [ 21]; however, many examples of cancer-specific gene isoforms (CD44, BRCA1, survivin etc), whose expression seem to correlate with the disease, have been described in literature [ 22].
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