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There are additional examples of associations with disease via genes in which there were frequent variants.
In addition, there are many documented examples of associations between iatrogenic hypoglycemia and death (3).
Vinyl chloride and bischloromethyl ether are examples of associations between single agents and rare histologic types of cancer.
Nevertheless, multiple empirical examples of associations between MHC variation and disease susceptibility [ 33- 35] highlight the potential susceptibility of populations of low MHC diversity to disease epidemics.
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To illustrate eQTLs with marginal effects, we show some examples of association SNPs using GenAMap (Curtis et al., 2012).
In this section, we shall consider the examples of association between binding avidity level and potential relation of nearby genes with stem-cell specific activity.
Indeed, the findings observed in our first cohort of patients, as those from Downie-Doyle and colleagues [ 3], were unexpected because there are only rare examples of association of the CTLA-4A/G*A allele with autoimmune diseases [ 5- 7].
Although examples of association between BRG1 and TFs have been previously described (Trotter and Archer, 2008; Reisman et al., 2009; Euskirchen et al., 2011), this specific configuration of BRG1 binding to nucleosomes flanking the TF binding sites has not been generally recognised.
For illustration, we present here examples of association results in the whole Generation R population obtained for two model phenotypes: (1) the dichotomous red hair pigmentation (a highly stratified trait) and (2) the continuous bone mineral density measured at the skull.
Amorphous pseudocyclic association schemes are examples of such association schemes whose associated symmetric design is trivial.
An example of association study of suboptimal health status and cardiovascular risk factors in urban Chinese workers[7].
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