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In both examples, interaction of ligand or an external challenge with membrane-associated receptors are considered to be key initiation events.
It has led to the discovery of one of the most reproducible examples: interaction between HLA-DRB1 SE and protein tyrosine phosphatase nonreceptor type 22 (PTPN22) risk genotypes and with smoking in anti-CCP+ patients [ 17].
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We present an envisioned example interaction, sketch the implemented Hadoop and spreadsheet level facilities, and describe the prototype the summarizer.
However, their approach cannot perform better than Ephraim and Malah's due to some coupled reasons (for example, interaction of estimation errors).
For example, interaction rate for LMV HMV would mean the number of LMVs found following or overtaking HMVs out of 1,000 LMVs observed in measurement area.
In other cases, for example, interaction of APOBEC3 with the proteins, Argonaute-1 and Argonaute-2, appeared not to be facilitated by RNA because the interaction was RNAse-resistant [29].
Concepts and terms already described in MIMix, for example "interaction detection method", "co-immunoprecipitation" were used as initial concepts in the construction of the SysPro ontology.
For example, interaction between PD-1 on T cells and PD-L1 on APCs regulates the development, maintenance and function of induced Treg (Francisco et al, 2009).
For example, interaction between chemokine stromal-derived factor 1α (SDF-1α) and its receptor C-X-C chemokine receptor type 4 (CXCR4) is of pivotal importance in this process.
For example, interaction dendrograms [ 7], an information theoretic visualization method and normalized mutual information [ 8] have been used with MDR [ 9] to investigate GGI and GEI.
For example, interaction of the MUC1 cytoplasmic tail with mitochondrial membrane, p53 or β-catenin prevents mitochondrion-mediated apoptosis in cell response to DNA damage.
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