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The importance of this class of proteins for nervous system development in humans is apparent from the large number of examples implicated in neurological or psychiatric disorders (reviewed in [ 49]).
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Genes investigated are, for example, implicated in serotonin and dopamine metabolism, neurogenic inflammation, vascular function, and hormone regulation.
Indeed, the selective pressure created by infection can be profound, with the evolution of genes for nitric oxide production, for example, implicated in a predisposition to diseases such as lupus and rheumatoid arthritis as well as defense against malaria [ 7].
We list a large number of putative examples of SNMs in Table 1 in the following section.> -wrap-foot> The first five examples are implicated in egalitarian transitions.
The other examples are implicated in fraternal transitions (Queller 1997) Social niche construction is a circular process in which organisms modify their own social niche in such a way as to influence the conditions of their own social evolution.
Other examples implicating copper in lignin biosynthesis include increased shikimate dehydrogenase and peroxidase activity observed in response to elevated copper concentrations leading to enhanced accumulations of phenolics and lignin in Capsicum annuum seedling hypocotyls [ 25].
Despite their importance, there are few examples implicating PTMs in plant immunity with phosphorylation, ubiquitination and sumoylation having received most attention in recent years.
Other examples implicate Leo1 Paf1 in transcriptional changes during development and inflammation [ 66].
Excessive speed, for example, is implicated in an overwhelming number of fatal crashes.
The power of the association was also investigated for long intergenic non-coding RNAs (lincRNAs), which are regulatory regions residing outside the exome that have for example been implicated in cancer13,14.
What features of the example are implicated in a given judgment are people reacting to the substance of the case, or the style of exposition?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com