The zoster vaccine, for example, has been tested only in older people.
He says that Joy, for example, has been tested in vivo on generations of women since its creation in 1930 "and nobody has complained".
The Office package, for example, has been tested by more than 3.5 million users; last month alone, more than 700,000 PC's were running the software, generating more than 46 million separate work sessions.
Facebook, for example, has been testing a feature that requires people to pay to send messages directly to people who are on Facebook but who have not agreed to be their "friends".
FedEx, for example, has been testing the API for a while now, and part of its store locator is already powered by it today.
HotelTonight, for example, has been testing out a campaign that it runs between 8 pm and 2 a.m. on streets dotted with bars and restaurants.
While numerous examples of these applications have been tested in vivo, the real deployments are far from reality.
Bowser and Hill give some examples of interventions that have been tested including: facility and system-wide quality-improvement initiatives; accountability mechanisms at the facility- and community-levels; protocols and training programs for providers; adaptation of childbirth interventions by communities; and rights and legal campaigns at the national-level [ 5].
I even use myself as an example, telling people I have been tested".
These days, the situation is often reversed; important new therapies — for example, Gleevec and Avastin — have been tested on adults first.
