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While some specific examples for network reduction of genome-scale models have been described in the literature [ 10, 12, 13], we are not aware of an automated and flexible network reduction approach that can generically be applied to any metabolic network.
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An example for networks with an intruder can be a wireless network with static wireless nodes, quasi-free-space channel properties such as the ones observed in wireless sensor networks deployed in large areas [28].
Examples for different networks are used to testify the usefulness of the method so we present some comparison tests.
Fig. 3 Example of network for the proposed method.
Fig. 1 Example for cellular network topology with outband D2D communications.
Figure 3 An example for opportunistic network coding with relay selection.
For example, for a network with eight genes, there will be 240=1.1×1012 trajectories after only k=4 time points.
For example, for the network depicted in Figure 1, Z = 2 0 1 0 1 0 2 0 0 1 0 0 0 0 0 1.
The strategy is illustrated by two examples for heat exchanger network synthesis.
JWS online [ 21], for example, provides a mechanism for network visualization using a force-directed layout algorithm [ 41, 42].
With more complex networks the numbers are still high, for example, 67.9% for networks with originally 10 interacting genes, which is significantly greater than the 14% rate for randomly generated networks with 9 interacting genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com