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Differences between SRAP expression in different subgroups (such as ER positive versus ER negative or node positive versus node negative, for example) were tested using the Mann-Whitney rank sum test, two sided.
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Some design examples are tested using the new method and their results are compared to those of PSO, PSOPC and HPSO algorithms to demonstrate the effectiveness of the present method.
Case studies are presented to illustrate the feasibility of the approach, and the model was tested using several examples, the results of which are consistent with existing data in the literature.
TCOB has been implemented and all examples presented in this paper were tested using this implementation.
For example, 5hmC can be tested using Tet-assisted bisulphite sequencing (TAB-seq [ 20]) or oxidative bisulphite sequencing (oxBS-seq [ 21]), with chemical modification-assisted bisulphite sequencing (CAB-seq) developed for 5caC [ 22], and reduced bisulphite sequencing (redBS-seq) for 5foC [ 23].
For example, overall visual system function was tested using protocols designed to characterize tectum-dependent and thalamus-dependent visual behaviors (Dong et al., 2009).
The SENB software was tested using examples from scientific literature.
The framework was trialled in small groups: two scientists and two statisticians worked in each group and the framework was tested using examples supplied by the scientists.
Thus, different values for the traffic load are tested (using, for example, the well-known bisection algorithm).
For example, relevant neurodevelopmental end points can be tested using assays of schedule-controlled behavior, attention and associative processing, spatial learning, and behavioral inhibition (Rice and Barone 2000).
Our method is tested using benchmark examples for three-dimensional potential problems.
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