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For example, the membrane adaptor molecule AP-1 interacts with MHC-I and is implicated in the Nef-dependent internalization of MHC-I8.
The use of genetically encoded light-activated proteins (for example, ion channels) to control functional parameters (for example, the membrane potential) of targeted neuronal populations.
For example, the membrane with IEC of 1.54 mequiv/g showed σ values of 81 and 11 mS/cm in water and 70% RH, respectively, at 60 °C.
For example, the membrane with IEC of 1.77 meq g−1 exhibited σ values of 120 and 260 mS cm−1 at 60 and 120 °C, respectively, in water.
For example, the membrane protein caveolin-1 has been implicated in many cell signaling pathways and diseases, yet the full-length protein is too aggregation-prone for detailed mutagenesis, directed evolution, and biophysical characterization.
For example, the membrane protein FTT_0583 was observed to be immunoreactive in two discrete protein spots, differing in both MW and pI (Figure 1a & b).
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For example, the membrane-bound pools of pyruvate dehydrogenase complex (PDHC) and α-ketoglutarate dehydrogenase complex (KGDHC) about 200 times exceed the "soluble" pool of these enzymes in the matrix [ 133].
For example, if the membrane potential recorded at time t is –70 mV, and the value that was sampled 125,000 steps before was –60 mV, a frequency of 25 kHz would give a momentum of –20 mV/s, which means that around time t the membrane tends to hyperpolarize at a rate of some –20 mV every second.
A good example is the membrane protein UBXD8 (also called FAF2, or Ubx2 in yeast) that recruits p97-Ufd1-Npl4 p97-Ufd1-Npl4 p97-Ufd1-Npl4retoculum-associated degradation [ 2].
Amphipols may restrict large-scale movements of transmembrane helices, for example in the membrane arm of complex I, and lock the assembly in a unique conformation, which would be an advantage for single-particle cryo-EM studies.
It has been shown for example that the membrane permeabilizing activity of Cry1Ac protoxin is significantly higher for the posterior than for the anterior regions of lepidopteran larvae; although no significant difference in the binding parameters for the protoxin were detected [ 71].
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