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As an example, the characterization of a real target is presented for later use.
For example, the characterization of community structure in the human brain network contributes to the identification of the anatomical and functional structures of brain regions associated with specific biological functions [16], [17], [18], [19], [20].
If we take as an example the characterization of ovarian tumors, diagnostic models have consistently focused on predicting malignancy versus benignity [ 2- 5].
For example, the characterization of FAD2 and FAE1 in C. sativa could enable the use of TILLING techniques to isolate C. sativa plants with mutations in each of the three identified copies of both genes.
For example, the characterization of an Arabidopsis EXCESS MICROSPOROCYTES 1 (EXS/EMS1) orthologue in rice (MULTIPLE SPROPOROCYTES I - MSPI) and subsequent delineation of its interaction with the TAPETUM DETERMINANT 1 (TPD1) rice orthologue (OsTDL1A), revealed its novel function in restricting the number of sporogenous cells in the ovule as well as in the anthers [ 2, 7- 10].
Metabolite dynamics have also been studied using FRET sensors leading to, for example, the characterization of sugar transport in roots of intact seedlings (Deuschle et al., 2006; Chaudhuri et al., 2008, 2011; Grossmann et al., 2011; Grossmann et al., 2012) and the identification of novel sugar transporters (Chen et al., 2010, 2012; Xuan et al., 2013).
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Among the various approaches that have been used for this scope, we recall for example the characterizations of multistationarity of [ 17], stability [ 18], and the boolean network analysis of e.g. [ 10, 19, 20].
A classic example is the characterization of Mozart in Peter Schaffer's 1979 play "Amadeus," where the composer produces music too advanced to be understood by a boorish public, meanwhile crawling on the floor and making bathroom jokes.
This technique has been extremely valuable, for example, in the characterization of the human microbiota in terms of lean and obese physiological states, impact of antibiotics, and the importance of delivery mode at birth [26], [27], [28].
For example, consider the characterization of sleep onset.
An emblematic example is the characterization of intracellular cargo transport on microtubules.
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