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Sections 5 and 6 contain a numerical example, sensitivity analysis and conclusion as a summary of findings and some future researches.
This includes for example sensitivity analysis or parameter optimization tasks such as identifiability analysis or estimation.
COPASI also allows closed-loop applications of parameter scanning, sampling and optimisation with one of the other analyses, for example sensitivity analysis or the linear noise approximation.
In the fourth numerical example, sensitivity analysis with respect to modal properties is applied to a full satellite model as shown in Fig. 14.
For example, sensitivity analysis can be useful for dealing with statistical uncertainty, but is less suitable for recognized ignorance (see for an explanation of these terms the following paragraph).
For example, sensitivity analysis provides information on the effect of changes in parameters (such as binding affinities) on the state of model variables (such as the phosphorylation of key protein).
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They qualitatively argue how those feedbacks might change at different spatiotemporal scales and use an example from a model sensitivity analysis to demonstrate the potential magnitude of this 'island effect'.
"Numerical example and sensitivity analysis," several numerical examples are given to illustrate the solution procedure and sensitivity analyses are performed.
The 'Numerical example and sensitivity analysis' section includes the numerical example and sensitivity analysis on the key parameters of the model.
The use of the model is illustrated using numerical example, and sensitivity analysis shows that the resultant optimum ALT plan is robust to the deviation in model parameters.
For example, a sensitivity analysis of the formaldehyde model (Crump et al. 2008) showed that small modifications to the model that did not affect its agreement with data could produce estimates of low-dose risk ranging from negative up to values far larger than risks predicted by the U.S. EPA default method based on linear extrapolation from a point of departure (U.S. EPA 2005).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com