Another example of a differentiated tissue is the skeletal tissue of a long bone, which contains osteoblasts (large cells that synthesize bone) in the outer sheath and osteocytes (mature bone cells) and osteoclasts (multinucleate cells involved in bone remodeling) within the matrix.
To our knowledge, CD40-stimulated B cells are the first example of a differentiated cell type from healthy human donors that undergoes conditional immortalization in vitro, in the absence of genetic manipulation.
The estuarine seaweed Fucus ceranoides provides a good example of highly differentiated populations along its most persistent distributional range at the present rear edge of the species distribution, in NW Iberia.
For example, one of the first differentiated roles of tapetal cells is to secrete callase to remodel the callose coat of PMC cells (Wang et al. 2010a) prior to meiosis; the tapetum is also the likely source of nutrients for the AR, PMC, and developing pollen.
For example, by emphasizing the differentiated nature of knowers one strengthens the argument for the epistemic interdependence of knowers; interaction between knowers becomes crucial so that individuals can access knowledge beyond the reach of their specific social location.
This picture would cast pluripotency as another example of a "differentiated" state maintained by positive feedback.
The adult mammalian cardiomyocyte cell is a "textbook example" of a terminally differentiated, non-dividing cell [ 48].
Figure 2a shows an example of a moderately differentiated HIT with many cystic papillary areas.
Impersonal cultural accounts of construction are also found in explanations of nonrepresentational phenomena, for example, of sex-differentiated behavior.
The whole cytogenetic and immunohistochemical pattern of tumours with 7p-gains, and to a lesser extent 5p-gains as well as 9q-losses (see also cluster in Figure 2), therefore puts them forward as putative examples of poorly differentiated tumours originating from well-differentiated tumours that have acquired a high degree of cytogenetic instability.
