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Constitutive ER transcriptional regulatory activity is an example of pathway bypass: it leads to cell cycle progression and activates the anti-apoptotic protein BCL2.
Currently the AV, and most of the research surrounding it, is probably the most outstanding example of Pathway A, where all efforts are focused on technological developments to decouple mobility from emission of Green House Gases (GHG) and air pollutants.
SBP wrote the example of pathway enumeration.
In this paper, we describe the first example of pathway analysis coupled with the DNA methylome of various tumor types.
Similarly, the miR-520 family was shown to suppress both NFκB and TGFβ signaling in breast cancer cells, providing another example of pathway co-regulation by miRNAs [ 41].
In conclusion, this example of pathway crosstalk provides a reference to biologists on how to control metabolic products to improve desired plant traits in metabolic engineering.
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The results represent a valid example of pathway-based data mining discovery.
We can also find example of pathways that have been lost in a lineage-specific manner.
They found that many of their candidate BPMs were enriched over certain Gene Ontology (GO) categories of protein function [12], and correlated well with some biologically-known examples of pathway buffering.
Examples of pathway frequency maps are depicted in Figure 3A and 3C.
Other examples of pathway topology based algorithms include impact factor based methods [ 12], NetGSA [ 13], ScorePAGE [ 14].
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