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The most intriguing example of overlapping relationships involves three key players who were represented by a little-known but ubiquitous American lawyer named Adam Waldman.
eRF3 is the only known protein with two high affinity PAM2 sites and the only example of overlapping sites.
The Surfeit locus contains another example of overlapping genes.
(A ) Example of overlapping transcripts from a convergent gene pair.
This is another example of overlapping patterns between observations in wild birds and in humans, as blaCTX-M-15 is also the most common CTX-M variant in humans in Sweden [ 3, 44].
Another example of overlapping TFBS is the GT dinucleotide within the ETS motif (C/GCGGAA GT) overlapping with the GT dinucleotide in the palindromic CRE motif (GTGACGTCAC) to produce the ETS↔CRE motif (C/GCGGAA GTGACGTCAC), which localizes to proximal promoters in mammals (Chatterjee et al. 2011; Rozenberg et al. 2013).
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Examples of overlapping and non-overlapping relaxed BSC sister species ranges are shown in Fig. 3.
Another example, in this case of overlapping TRAPS/CAPS phenotype, was described in 2006 of a 36-year-old French woman and her mother, both with NLRP3 V198M and TNFRSF1A R92Q.
We use the xrate phylo-grammar engine wherever possible (for example, resolution of overlapping gene predictions on opposite strands follows automatically if a strand-symmetric grammar is used).
They were missed by our CNV calling algorithm because of their complex nature: for example, presence of overlapping or closely neighboring CNVs in both parents in the CNV region (Additional file 10C).
Our methods were either developed specifically for Tara Oceans samples or carefully selected among existing ones in order to meet the requirements of our sequencing strategy and to produce optimized datasets for downstream bioinformatics analyses, as for example the production of overlapping reads from metagenomics libraries to facilitate assembly.
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Justyna Jupowicz-Kozak
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