Cutaneous lupus erythematosus (CLE), DM, and PV are three examples of autoimmune dermatoses that either lack or until recently lacked validated outcome measures.
Thus, although genetic predisposition plays an important role in pathogenesis of this autoimmune disorder, like other examples of autoimmune disease, exposure to infectious agents also has an important part in the development of this disorder (for review [ 57]).
Some examples of autoimmune diseases are autoimmune hepatitis, type I diabetes mellitus, rheumatoid arthritis (RA), Sjögren's syndrome, systemic lupus erythematous, multiple sclerosis (MS), psoriasis and inflammatory bowel disease (Crohn's disease and ulcerative colitis) (Beyaert et al., 2013).
There exist several examples of autoimmune diseases resulting from oxidative modifications of self-proteins, namely, systemic lupus erythematosus (60 kD Ro ribonucleoprotein) [ 118], diabetes mellitus (high molecular weight complexes of glutamic acid decarboxylase) [ 119], and diffuse scleroderma (oxidation of beta-2-glycoprotein) [ 120, 121].
Sjogren's syndrome, systemic lupus erythematosus, rheumatoid arthritis, Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy are some examples of autoimmune diseases.
For example, models of autoimmune diseases involving the central nervous system have been developed in the common marmoset and it has been used extensively as a primate model.
Two patients (patients 10 and 11) with no rearrangement of TCR genes may serve as examples of autoimmune-disease-related, polyclonal, reactive, chronic proliferation of LGL lymphocytes.
However, even well-evolved systems can go wrong and, just as the immune system occasionally attacks the body it is supposed to be defending, causing a so-called autoimmune disease, so it looks as though the TNF-α fatigue response may sometimes appear at the wrong time.One example of an autoimmune disease is rheumatoid arthritis.
They found reduced levels of sAPPα/β compared to controls, but the reductions in sAPP products seem not to be specific to MS because of similar results seen in Lupus erythematodes as an example of another autoimmune disease [35].
