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The drug imatinib is another example of a targeted therapy.
Parent child Interaction Therapy (PCIT) is an example of a targeted program that aims to reduce the incidence of child maltreatment in physically abusive parents.
This is the first example of a targeted chromosomal deletion generated by homologous recombination in this genus and the resulting mutant, JWCB018 (Δ pyrFA Δ cbeI), is readily transformed by DNA isolated from E. coli without in vitro methylation.
Gefitinib ('Iressa', ZD1839), an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is an example of a targeted agent that has demonstrated favourable tolerability and durable antitumour activity in clinical trials in patients with advanced NSCLC (Fukuoka et al, 2003; Kris et al, 2003).
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One exciting example of a rational, targeted approach to breast cancer treatment is HerceptinTM (Genentech, San Francisco, California, USA), a recombinant humanized antibody targeted to ErbB2.
As an independent mobile marketing consultant, I am starting to see some interesting examples of trigger marketing in action: One of the major mobile providers in the UK, Orange, launched the Orange Wednesday campaign, which is a great example of a sensibly targeted campaign that identifies a genuine interest and creates an exemplary user experience to close the deal.
Shigella thus provides an example of a bacteria targeted to autophagosomes via a combination of ubiquitin-independent (i.e. recognized by ATG5 TECPR1) and ubiquitinated (i.e. recognized by autophagy receptors) signals (Fig. 2).
"The licence fee collection regime is a classic example of a target regime that has gone abysmally wrong," he added.
Fig. 1 Example of a target-present image.
Anchor 54 is representative for a target in the center of the building, and anchor 55 is a good example of a target in an extremity of the building.
Firstly, we take silicon as an example of a target material; should a regular continuous wave laser be focused onto its surface, with an arbitrary energy just above its bandgap, one would observe the excitation of electrons to the conduction band through an indirect process involving phonons.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com