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Insurance is the classic example of a mechanism for spreading the risk of financial disaster, but recently, investment companies have introduced much more sophisticated mechanisms.
We provide a stark example of a mechanism design problem in a collective choice environment with information acquisition.
Recent studies have revealed that AID's DNA mutator activity is regulated by the RNA exosome complex, thus providing an example of a mechanism that relates DNA mutagenesis to RNA processing.
HGT is one example of a mechanism that causes branching histories at different levels of organization to be incongruent.
Supportive leadership can make a staff member feel valued and important at the workplace, and is thus an example of a mechanism that may nourish intrinsic motivation.
This is again an example of a mechanism that could help a complex biological system maintain its physiological function in spite of genetic interventions.
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Optimisation of the properties of kinase inhibitors identified by HTS has led to perhaps the currently best-known example of a mechanism-based, genome-targeted cancer drug.
14α-Methylenecyclopropyl-Δ7-24,25-dihydrolanosterol (LNP) was reported as a substrate-based analogue, which tightly binds to all protozoan CYP51 but acts as a suicide substrate for T. cruzi CYP51, providing an example of a mechanism-based CYP51 inhibitor.
However, there is no example of such a mechanism in the aetiology of cancer.
A well-described example of such a mechanism is the inactivation of the X chromosome in mammals (Lyon 1974).
A good example of such a mechanism is the binding of substrate to CDK-cyclin complexes, where the cyclin must bind to CDK before the substrate [ 30].
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