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54, 55 A classic example of a DNA repair gene downregulated by DNA methylation is the MGMT gene, which is silenced by epigenetic mechanisms in brain tumors.
To our knowledge, however, there is no example of a DNA barcode reference data set that covers a whole country for any taxonomic group above the family level.
An example of a DNA damage assay involves scoring radiation-induced gammaH2AX foci [ 43].
Our data represents the first example of a DNA bound multi-protein complex which can slide along another DNA to facilitate target search.
RecA-mediated homology search is the first example of a DNA bound multi protein complex which can slide on another DNA during target search process.
MGMT is another good example of a DNA repair gene undergoing methylation-mediated inactivation in human cancer [ 25], including GBM [ 26].
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One example of a DNA-based community fingerprinting approach that has been used to study antibiotic effects on the gut microbiota is terminal restriction fragment length polymorphism (T-RFLP) [29].
Next to actinomycin D as one of the most prominent examples of a DNA binding peptidic natural product used in anti-cancer therapy (Farber 1966; Lewis 1972), the quinoxaline antibiotics echinomycin, thiocoraline, and triostin A (1) are well established (Lee and Waring 1978; Waring and Wakelin 1974).
It represents an example of a human DNA virus directly using the macroautophagy machinery to build its infectious particles and to incorporate Atg8/LC3 coupled membranes into them.
In another example, conjugation of a DNA-binding protein to PNIPAAm was employed to form a biofunctional hydrogel, permitting the production of materials that retain the ability to bind specific DNA.
We focus on doxorubicin as example of a classical cytotoxic, DNA damaging agent and on sunitinib, as example of the new generation of (receptor) tyrosine kinase-targeted agents.
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CEO of Professional Science Editing for Scientists @ prosciediting.com