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For example, mice with depleted microbiomes appear to be more susceptible to the flu.
For example, mice, with their big litters, need a higher-performing placenta than humans do--one that has a larger number of hormones and enzymes involved in embryonic nutrition, Knox and Baker report in the May issue of Genome Research.
For example, mice with inactivation of perlecan, an ECM protein required for collagen fibril assembly, fail to organize cartilage growth plates after the mesenchymal condensation stage and the phenotype progressively worsens as development progresses.
3 For example, mice with mosaic deletion of Atg5 and liver-specific Atg7 developed multiple liver tumors.
For example, mice with deletion of ALDH1A3 (Cluster 5), a key factor regulating synthesis of retinoic acid, die just after birth due to altered epithelial mesenchymal development (58).
For example, mice with reduced IGF-I activity (hemizygous for the IGF-I receptor) have lower levels of ROS in the brain.
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For example, mice treated with docetaxel in combination with repertaxin, a CXCR1/2 small-molecule inhibitor, exhibited a reduction in the CD44+/CD24-population CD44+/CD24-populationary tumors and a decrease in systheir metastases [ 91].
For example, mice infected with C. difficile could be cured with feces from healthy mice (Lawley et al. 2012), in accordance with the successful treatment of human relapsing C. difficile colitis.
For example, mice infected with H. pylori for six months have an increased frequency of gastric mutations compared to uninfected mice [5].
For example, mice immunized with an HSV-2 gD subunit vaccine mount a gD2-antibody response that is 20-fold greater than that elicited by immunization of mice with HSV-2 0ΔNLS (unpublished data of W. Halford).
For example, mice inoculated with HSV-2 0ΔRING shed peak titers of virus that were ∼1% of the peak titers shed by HSV-2 MS-infected mice and mounted gD2-antibody responses that were ∼0.5% of that in HSV-2 MS-infected mice (Fig. 5, 6).
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